男， 1965 年 7 生于四川资中。
1983.09-1987.07, 四川大学化学系读本科
1987.09-1993.03, 四川大学化学系有机专业攻读硕士、博士学位。
1993.04-1994.09: 四川大学化学系任讲师
1994.10-1999.06: 四川大学化学系任副教授
1998.04-2001.03: 香港大学化学系支志明院士研究室 Research Associate
1999.07- 至今： 四川大学化学学院教授、博士生导师 1 、化学生物学（生物材料化学）
2 、有机化学（生物有机化学）
3 、绿色化学（绿色合成方法学） (1). Zhang, Q.-F., Yi, W.-J., Wang, B., Zhang, J.*, Ren, L.-F., Chen, Q.-M., Guo, L.-D.*, Yu, X.-Q.*, Linear polycations by ring-opening polymerization as non-viral gene delivery vectors, Biomaterials, 2013, 34, 5391-5401.
(2). Xie, Z.-B., Wang, N.*, Zhou, L.-H., Wan, F., He, T., Le, Z.-G., Yu, X.-Q.*, Lipase-Catalyzed Stereoselective Cross-Aldol Reaction Promoted by Water, ChemCatChem, 2013,5, 1935–1940.
(3). Du, J., Huang, Z., Yu, X.-Q.*, Pu, L.*, Highly selective fluorescent recognition of histidine by a crown ether–terpyridine–Zn(II) sensor, Chem. Commun., 2013, 49, 5399--5401.
(4). Chen, W., Tay, J.-H. Ying, J., Sabat, M., Yu, X.-Q.*, Pu, L.*, A quick access to the spirotricyclic core analogue of mangicol A by a Rh( I )-catalyzed tandem Pauson–Khand/[4+2] cycloaddition, Chem. Commun., 2013, 49, 170-172.
(5). Feng, J., Yang, X.-B., Liang, S., Zhang, J.*, Yu, X.-Q.*, An efficient oxidative coupling method for synthesis of novel diastereomeric biaryl diols derived from estrone, Tetrahedron Lett. 2013, 54, 355–357.
(6). Xie, Z.-B., Wang, N.*, Jiang, G.-F., Yu, X.-Q.*, Biocatalytic asymmetric aldol reaction in buffer solution, Tetrahedron Lett. 2013, 54, 945–948.
(7). He, T., Li, K.*, Wu, M.-Y., Wu, M.-B., Wang, N., Pu, L., Yu, X.-Q.*, Water promoted enantioselective aldol Reaction by proline-cholesterol and -diosgenin based amphiphilic organocatalysts, Tetrahedron, 2013, 69, 5136-5143.
(8). Hou, J.-T., Li, K.*, Liu, B.-Y., Liao, Y.-X., Yu, X.-Q.*, The first ratiometric probe for lysine in water, Tetrahedron, 2013, 69, 2118-2123.
(9). Hou, J.-T., Li. K.*, Yu, K.-K., Wu, M.-Y., Yu, X.-Q.*, Coumarin–DPA–Cu(II) as a chemosensing ensemble towards histidine determination in urine and serum, Org. Biomol. Chem., 2013, 11, 717-720.
(10). Xun, M.-M., Zhang, X.-C., Zhang, J.*, Jiang, Q.-Q., Yi, W.-J., Zhu, W.*, Yu, X.-Q.*, Low molecular weight PEI-based biodegradable lipopolymers as gene delivery vectors, Org. Biomol. Chem., 2013, 11, 1242–1250.
(11). Tao, F-Y., Wang, C.-G., Ma, K.-Y., Li, D.-L., Tan, L.-L., Zhang, J., Dai, Y.*, Yu, X.-Q.*, A facile synthesis and application of protoporphyrin derivatives on reducing the tobacco specific N-nitroamines levels of smoke, J. Porphyrins Phthalocyanines 2013, 17, 309–316.
(12). Zhou, L.-H., Wang, N.*, Zhang, W., Xie, Z.-B., Yu, X.-Q.*, Catalytical promiscuity of a-amylase: Synthesis of 3-substituted 2H-chromene derivatives via biocatalytic domino oxa-Michael/aldol condensations, J. Mol. Catal. B: Enzym., 2013, 91, 37–43.
(13). Lu, Q.-S., Hou, J.-T., Wang, J., Xu, B.-Y., Zhang, J.*, Yu, X.-Q.*, Multichannel Chromogenic and Chiral Anions Recognition by Imidazolium Functionalized BINOL Derivatives, Chin. J. Chem. 2013, 31, 641-650.
(14). Zhou, Y.-J., Hu, C.-L., Wang, N.*, Zhang, W.-W., Yu, X.-Q.*, Purification of porcine pancreatic lipase by aqueous two-phase systems of polyethylene glycol and potassium phosphate, J. Chromatography B, 2013, 926, 77–82.
(15). Chen, W., Tay, J.-H. Ying, J., Yu,,X.-Q.*, Pu, L.*, Catalytic Asymmetric Enyne Addition to Aldehdyes and Rh(I)-Catalyzed Stereoselective Domino Pauson − Khand/[4 + 2] Cycloaddition, J. Org. Chem. 2013, 78, 2256 – 2265.
(16). Li, K., Xu, H.-R., Yu, K.-K., Hou, J.-T., Yu, X.-Q.*, A coumarin-based chromogenic and ratiometric probe for hydrazine, Anal. Methods, 2013, 5, 2653-2656.
(17). Liu, Q., Jiang, Q.-Q., Yi, W.-J., Zhang, J.*, Zhang, X.-C., Wu, M.-B., Zhang, Y.-M., Zhu, W.*, Yu, X.-Q.*, Novel imidazole-functionalized cyclen cationic lipids: Synthesis and application as non-viral gene vectors, Bioorg. Med. Chem. 2013, 21, 3105–3113.
(18). Wu, M.-Y., He, T., Li, K.*, Wu, M.-B., Huang, Z., Yu, X.-Q.*, A real-time colorimetric and ratiometric fluorescent probe for sulfite, Analyst, 2013, 138, 3018–3025.
(19). Xu, H.-R., Li, K.*, Liu, Q., Wu, T.-M., Wang, M.-Q., Hou, J.-T., Huang, Z., Xie, Y.-M.*, Yu, X.-Q.*, Dianthracene–cyclen conjugate: the first equal-equivalent responding fluorescent chemosensor for Pb2+ in aqueous solution, Analyst, 2013, 138, 2329–2334.
(20). Jiao, S.-Y., Peng, L.-L., Li, K.*, Xie, Y.-M., Ao, M.-Z., Wang, X.*, Yu, X.-Q.*, A BINOL-based ratiometric fluorescent sensor for Zn2+ and in situ generated ensemble for selective recognition of histidine in aqueous solution, Analyst, 2013, 138, 5762-5768.
(21). Xie, Z.-B., Wang, N.*, Wu, M.-Y., He, T., Le, Z.-G., Yu, X.-Q.*, Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method, Beilstein J. Org. Chem., 2012, 8, 534–538.
(22). Huang, Z., Du, J., Zhang, J., Yu, X.-Q.*, Pu, L.*, Highly selective fluorescent recognition of Zn2+ in water by terpyridine–CuCl2, Anal. Methods, 2012, 4 , 1909-1912.
(23). Feng, J., Liang, S., Chen, S.-Y., Zhang, J.*, Fu, S.-S., Yu, X.-Q.*, A Metal-Free Oxidative Esterification of the Benzyl C-H Bond, Adv. Synth. Catal., 2012, 354, 1287-1292.
(24). Zhang, W.-W., Wang, N.*, Zhou, Y.-J., He, T., Yu, X.-Q.*, Enhancement of activity and stability of lipase by microemulsion-based organogels (MBGs) Immobilization and application for synthesis of arylethyl acetate, J. Mol. Catal. B: Enzymatic, 2012, 78, 65–71.
(25). Li, S., Wang, Y., Wang, S., Zhang, J.*, Wu, S.-F., Wang, B.-L., Zhu, W.*, Yu, X.-Q.*, Biodegradable cyclen-based linear and cross-linked polymers as non-viral gene vectors, Bioorg. Med. Chem., 2012, 20, 1380–1387.
(26). Huang, Q.-D., Ren, J., Ou, W.-J., Fu, Y., Cai, M.-Q., Zhang, J.*, Zhu, W.*, Yu, X.-Q.*, Cationic Lipids Containing Cyclen and Ammonium Moieties as Gene Delivery Vectors, Chem. Biol. Drug Des., 2012, 79, 879-887.
(27). Wu, M.-Y., Li, K*, Hou, J.-T., Huang, Z., Yu, X.-Q.*, A selective colorimetric and ratiometric fluorescent probe for hydrogen sulfide, Org. Biomol. Chem., 2012, 10, 8342-8347.
(28). Chen, W., Tay, J.-H., Yu, X.-Q.*, Pu, L.*, Diastereoselective [4 + 1] Cycloaddition of Alkenyl Propargyl Acetates with CO Catalyzed by [RhCl(CO)2]2, J. Org. Chem., 2012, 77, 6215−6222.
(29). Wang, M.-Q., Li, K.*, Hou, J.-T., Wu, M.-Y., Huang, Z., Yu, X.-Q.*, BINOL-Based Fluorescent Sensor for Recognition of Cu(II) and Sulfide Anion in Water, J. Org. Chem., 2012, 77, 8350−8354.
(30). Wen, J., Zhang, R.-Y., Chen, S.-Y., Zhang J.*, Yu, X.-Q.*, Direct Arylation of Arene and N-Heteroarenes with Diaryliodonium Salts without the Use of Transition Metal Catalyst, J. Org. Chem., 2012, 77, 766-771.
(31). Huang, Q.-D., Ren, J., Chen, H., Ou, W.-J., Zhang, J.*, Fu, Y., Zhu, W.*, Yu, X.-Q.*, Cyclen-Based Cationic Lipids Containing Carbamate Linkages as Efficient Gene Delivery Vectors with Low Toxicity, ChemPlusChem, 2012, 77, 584-591.
(32). Huang, Z., Du, J., Zhang, J., Yu, X.-Q.*, Pu, L.*, A simple and efficient fluorescent sensor for histidine, Chem. Commun., 2012, 48, 3412-3414.
(33). Wang, J., Wang, S., Wang, G., Zhang, J.*, Yu, X.-Q.*, Iron-mediated direct arylation with arylboronic acids through an aryl radical transfer pathway, Chem. Commun., 2012, 48, 11769–11771.
(34). Zhang, Y., Huang, Y., Zhang, J., Zhang, D.-W., Liu, J.-L., Liu, Q., Lin, H.-H.*, Yu, X.-Q.*, Synthesis, DNA binding and cleavage studies of the copper(II) complexes of PNA-cyclen conjugates, Sci. China Chem., 2011, 54(1), 129-136.
(35). Zhang, Y., Wang, M.-Q., Zhang, J., Zhang, D.-W., Lin, H.-H.*, Yu, X.-Q.*, Synthesis, DNA Binding, and Cleavage Studies of Novel PNA Binding Cyclen Complexes, Chem. Biodivers., 2011, 8, 827-840.
(36). Huang, Z., Chen, X., Zhang, J., Yu,X.-Q.*, Pu, L.*, Connecting BINOL and Terpyridine: The Electronic Effects of the Linkage, Tetrahedron Lett., 2011, 52, 5497–5500.
(37). Wu, M.-Y., Wang, M.-Q., Li, K.*, Feng, X.-W., He, T., Wang, N., Yu, X.-Q.*, An efficient, transition-metal-free process for the synthesis of substituted dihydrofurans via a Michael/cyclization tandem reaction, Tetrahedron Lett. 2011, 52, 679–683.
(38). Wu, M.-Y., Li, K.*, He, T., Feng, X.-W., Wang, N., Wang, X.-Y., Yu, X.-Q.*, A novel enzymatic tandem process: utilization of biocatalytic promiscuity for high stereoselective synthesis of 5-hydroxyimino-4,5-dihydrofurans, Tetrahedron, 2011, 67, 2681-2688.
(39). Du, X., Wang, Q.*, He, X., Peng, R.-G., Zhang, X., Yu, X.-Q.*, Highly enantioselective addition of linear alkyl alkynes to aromatic aldehydes, Tetrahedron: Asymmetry, 2011, 22, 1142–1146.
(40). Hou, J.-T., Zhang, Q.-F., Xu, B.-Y., Lu, Q.-S., Liu, Q., Zhang, J., Yu, X.-Q.*, A novel BINOL-based cyclophane via click chemistry: synthesis and its applications for sensing silver ions, Tetrahedron Lett., 2011, 52, 4927–4930.
(41). Ye, Y.-H., Zhang, J., Wang, G., Chen, S.-Y.*, Yu, X.-Q.*, Cobalt-catalyzed benzylic CeH amination via dehydrogenative-coupling reaction, Tetrahedron, 2011, 67, 4649-4654.
(42). Wang, M.-Q., Zhang, J., Zhang, Y., Zhang, D.-W., Liu, Q., Liu, J.-L., Lin, H.-H.*, Yu, X.-Q.*, Metal-free Cleavage Efficiency toward DNA by a Novel PNA Analog-bridged Macrocyclic Polyamine, Bioorg. Med. Chem. Lett., 2011, 21, 5866-5869.
(43). Yi, W.-J., Feng, Z.-H., Zhang, Q.-F., Zhang, J.*, Li, L.-D., Zhu, W.*, Yu, X.-Q.*, Diol glycidyl ether-bridged cyclens: preparation and their applications in gene delivery, Org. Biomol. Chem., 2011, 9, 2413-2421.
(44). Li, S., Wang, Y., Zhang, J.*, Yang, W.-H., Dai, Z.-H., Zhu, W.*, Yu, X.-Q.*, Biodegradable cross-linked poly(amino alcohol esters) based on LMW PEI for gene delivery, Mol. BioSyst., 2011, 7, 1254-1262.
(45). Wu, M.-Y., Li, K.*, Wang, N., He, T., Yu, X.-Q.*, A Novel Catalyst-Free Tandem Reaction for the Synthesis of 5-Hydroxy-1,5-dihydro-2H-pyrrol-2-ones in Water Medium, Synthesis, 2011, 12, 1831–1839.
(46). Wang, H.-Y., Zhou, Y.-J., Wang, Z., Wang, N.*, Li, K., Yu, X.-Q.*, Enzyme-Catalyzed Synthesis of a Novel Thermosensitive Polyester with Pendant Ketoprofen, Macromol. Biosci., 2011, 11, 595–599.
(47). Huang, Q.-D., Ou, W.-J., Chen, H., Feng, Z.-H., Wang, J.-Y., Zhang, J.*, Zhu, W.*, Yu, X.-Q.*, Novel cationic lipids possessing protonated cyclen and imidazolium salt for gene delivery, Eur. J. Pharm. Biopharm., 2011, 78, 326–335.
(48). Huang, Q.-D., Zhong, G.-X., Zhang, Y., Ren, J., Fu, Y., Zhang, J.*, Zhu, W.*, Yu, X.-Q.*, Cyclen-Based Cationic Lipids for Highly Efficient Gene Delivery towards Tumor Cells, PLoS ONE, 2011, 6, e23134. doi:10.1371/journal.pone.0023134
(49). Liu, J.-L., Ma, Q.-P., Huang, Q.-D., Yang, W.-H., Zhang, J.*, Wang, J.-Y., Zhu, W., Yu, X.-Q.*, Cationic lipids containing protonated cyclen and different hydrophobic groups linked by uracil-PNA monomer: Synthesis and application for gene delivery, Eur. J. Med. Chem., 2011, 46, 4133-4141.
(50). Wang, M.-Q., Liu, J.-L., Wang, J.-Y., Zhang, D.-W., Zhang, J., Streckenbach, F., Tang, Z.*, Lin, H.-H.*, Liu, Y., Zhao, Y.-F., Yu,X.-Q.*, Site-selective DNA Hydrolysis Induced by a Metal-free Peptide Nucleic Acid-Cyclen Conjugate, Chem. Commun., 2011, 47, 11059-11061.
(51). Wang, J., Hou, J.-T., Wen, J., Zhang, J.*, Yu, X.-Q.*, Iron-catalyzed direct amination of azoles using formamides or amines as nitrogen sources in air, Chem. Commun., 2011, 47, 3652-3654.
(52). Zhang, Q.-F., Yang, W.-H., Yi, W.-J., Zhang, J.*, Ren, J., Luo, T.-Y., Zhu, W.*, Yu, X.-Q.*, TACN-containing cationic lipids with ester bond: Preparation and application in gene delivery Bioorg. Med. Chem. Lett., 2011, 21, 7045–7049.
(53). Wen, J., Fu, Y., Zhang, R.-Y., Zhang, J.*, Chen, S.-Y., Yu, X.-Q.*, A simple and efficient synthesis of pyrazoles in water, Tetrahedron, 2011, 67, 9618-9621.
(54). Lu, Q.-S., Zhang, J., Jiang, L., Hou, J.-T., Yu, X.-Q.*, Highly selective ratiometric estimation of fluoride ion based on a BINOL imidazolium cyclophane with dual-channel, Tetrahedron Lett., 2010, 51, 4395–4399.
(55). Feng, X.-W., Wang, J., Zhang, J., Yang, J., Wang, N., Yu, X.-Q.*, Copper-Catalyzed Nitrogen Loss of Sulfonylhydrazones: A Reductive Strategy for the Synthesis of Sulfones from Carbonyl Compounds, Org. Lett., 2010, 12, 4408-4411.
(56). Turlington, M., Yue, Y., Yu, X.-Q.*, Pu, L.*, Catalytic Asymmetric Synthesis of Chiral Propargylic Alcohols for the Intramolecular Pauson-Khand Cycloaddition, J. Org. Chem., 2010, 75, 6941–6952.
(57). Wang, L., Li, C., Wang, N.*, Li, K., Chen, X., Yu, X.-Q.*, Enzyme-mediated domino synthesis of 2-alkylbenzimidazoles in solvent-free system: A green route to heterocyclic compound, J.Mol. Catal.B: Enzym., 2010, 67, 16–20.
(58). He, T., Li, K.*, Wu, M.-Y., Feng, X.-W., Wang, N., Wang, H.-Y., Li, C., Yu, X.-Q.*, Utilization of biocatalytic promiscuity for direct Mannich reaction, J.Mol. Catal.B: Enzym., 2010, 67, 189–194.
(59). Qin, J., Meng, X.-W., Li, B.-J., Ha, W., Yu, X.-Q.*, Zhang, S.*, Self-assembly of b-cyclodextrin and pluronic into hollow nanospheres in aqueous solution, J. Colloid Interface Sci., 2010, 350, 447–452.
(60). Li, C., Zhou, Y.-J., Wang N.*, Feng, X.-W., Li, K., Yu, X.-Q.*, Promiscuous protease-catalyzed aldol reactions: A facile biocatalytic protocol for carbon–carbon bond formation in aqueous media, J.Biotech., 2010, 150, 539–545.
(61). Liu, Q., Zhang, J., Wang, M.-Q., Zhang, D.-W., Lu, Q.-S., Huang, Y., Lin, H.-H.*, Yu, X.-Q.*, Synthesis, DNA binding and cleavage activity of macrocyclic polyamines bearing mono- or bis-acridine moieties, Eur. J. Med. Chem., 2010, 45, 5302-5308.
(62). Wang, H.-Y., Zhang, W.-W., Wang, N.,* Li, C., Li, K., Yu, X.-Q.*, Biocatalytic Synthesis and in Vitro Release of Biodegradable Linear Polyesters with Pendant Ketoprofen Biomacromolecules, 2010, 11, 3290–3293.
(63). Chen, X., Huang, Z., Chen, S.-Y., Li, K., Yu, X.-Q.*, Pu, L.*, Enantioselective Gel Collapsing: A New Means of Visual Chiral Sensing, J. Am. Chem. Soc., 2010, 132, 7297–7299.
(64). Wen, J., Qin, S., Ma, L.-F., Dong, L., Zhang, J., Liu, S.-S., Duan, Y.-S., Chen, S.-Y., Hu, C.-W.*, Yu, X.-Q.*, Iron-Mediated Direct Suzuki-Miyaura Reaction: A New Method for the ortho-Arylation of Pyrrole and Pyridine, Org. Lett., 2010, 12, 2694-2697.
(65). Xiang, Y.-Z., Feng, Z.-H., Zhang, J.*, Liao, Y.-L., Yu, C.-J., Yi, W.-J., Zhu, W.*, Yu, X.-Q.*, Linear cyclen-based polyamine as a novel and efficient reagent in gene delivery, Org. Biomol. Chem., 2010, 8, 640–647.
(66). Chen, X., Chen, W., Wang, L., Yu, X.-Q.*, Huang, D.-S., Pu, L.*, Synthesis of a C1 symmetric BINOL–terpyridine ligand and highly enantioselective methyl propiolate addition to aromatic aldehydes, Tetrahedron, 2010, 66, 1990–1993.
(67). Chen, X., Liu, Q., Sun, H.-B., Yu, X.-Q.*, Pu, L.*, A BINOL–terpyridine-based multi-task catalyst for a sequential oxidation and asymmetric alkylation of alcohols, Tetrahedron Lett., 2010, 51, 2345–2347.
(68). Huang, Y., Liu, J.-L., Zhang, J., Liu, Q., Hou, J.-T., Zhang, Y., Zhang, D.-W., Lu, Q.-S., Chen, S.-Y., Lin, H.-H.*, Yu, X.-Q.*, Interaction of bis-aryl functionalized molecules with nucleosides and nucleic acids, Sci. China Chem., 2010, 53, 103–112.
(69). Zhou, L.-H., Yu, X.-Q.*, Pu, L.*, Reactivity of a propiolate dimer with nucleophiles and an efficient synthesis of dimethyl a-aminoadipate, Tetrahedron Lett., 2010, 51, 425–427.
(70). Zhou, L.-H., Yu, X.-Q.*, Pu, L.*, Na-promoted aerobic oxidation of alcohols to ketones, Tetrahedron Lett., 2010, 51, 475–477.
(71). Meng, X.-W., Qin, J., Liu, Y., Fan, M.-M., Li, B.-J.*, Zhang, S.*, Yu, X.-Q., Degradable hollow spheres based on self-assembly inclusion, Chem. Commun., 2010, 46, 643–645.
(72). Liu, P.-Y., Li, K.*, Zhang, J., Zhang, D.-W., Lin, H.-H.*, Yu, X.-Q.*, Who Is the King? The a-Hydroxy-b-oxo-a,b-enone Moiety or the Catechol B Ring: Relationship between the Structure of Quercetin Derivatives and Their Pro-Oxidative Abilities, Chem. Biodivers., 2010, 7, 236-244.
