将 "He wants to go home" 变成否定句需要在句子前加上 "He does not" 或缩写形式 "He doesn't",并在动词 "wants" 后加上 "to" 的否定形式 "not",变为 "He does not want to go home." 或 "He doesn't want to go home." 将 "He wants to go home" 变成一般疑问句需要在句首加上助动词 "Does",并将主语 "He" 放在助动词之后,变为 "Does he want to go home?"