区别在于含义的不同。
1、at school=in school指的是学生在学校上课。
2、in the school=at the school指的是在学校内任职，比如说老师，教导主任等
3、at school也可泛指，而in the school则特指某一所学校。
例句：
①I bet you were good at games when you were at school.
我敢说你上学时体育很棒。
②Should our children be taught to swim at school?
我们的孩子应该在学校学习游泳吗？
③He teaches English in the school all the while.
他一直在这所学校里教英语。
④She plays the flute in the school orchestra.
她在校管弦乐队里吹长笛。
扩展资料
相关句子：
1、There is a subdued atmosphere in the school at exam time.
在考试期间,学校里有一种压抑的氛围.
2、Police are investigating the suspected drug ring at the school.
警方正在调查这所学校的可疑贩毒团伙。
3、Ordinarily she sleeps at the school and goes home only on Saturdays.
她平时住在学校，星期六才回家。
4、Connie did well at school and graduated with honours.
康妮在学校表现很好，以优异的成绩毕业了。
at school, 表示在上学，固定用法，in the school, 在学校里。
一、at school
释义：在学校，在上课，在求学
拓展资料
1、He was disciplined at school for talking back to the teacher.
他因为和教师顶嘴受到了处分。
2、Each child had participated in extracurricular activities at school.
每个孩子都参加了学校的课外活动。
3、Is the child at school?
这孩子上学了吗？
4、Her class teacher made a special arrangement to discuss her progress at school once a month.
她班上的老师作了特别安排，每月讨论一次她在学业上的进展情况。
5、Science was never my strong point at school.
我上学时理科从来都不是我的强项。
二、in the school
释义：在学校;在这所学校
拓展资料
1、The pupils assembled in the school hall.
学生在学校礼堂集合。
2、He was the only boy in the school who was known by his Christian name and not his surname.
他是学校里唯一一个被称呼洗礼名而不是姓氏的男孩儿。
3、Just as the teacher plays the role of leader in the classroom, so does the headteacher play a leadership role in the school.
在课堂上老师扮演着领导者的角色，同样，在学校里校长也充当着领导者的角色。
4、She is considered the best in the school.
全校数她功课好。
5、The pupils assembled [ were assembled] in the school hall.
学生在礼堂会集。
本回答被网友采纳at school=in school在学校（特指学生在校学习），in the school=at the school在学校。at school表示的是学校的功能，in the school表示的是在学校这个地点。、
at school
1、He was disciplined at school for talking back to the teacher.
他因为和教师顶嘴受到了处分。
2、Each child had participated in extracurricular activities at school.
每个孩子都参加了学校的课外活动。
3、Is the child at school?
这孩子上学了吗？
4、Her class teacher made a special arrangement to discuss her progress at school once a month.
她班上的老师作了特别安排，每月讨论一次她在学业上的进展情况。
5、Science was never my strong point at school.
我上学时理科从来都不是我的强项。
in the school
1、The pupils assembled in the school hall.
学生在学校礼堂集合。
2、He was the only boy in the school who was known by his Christian name and not his surname.
他是学校里唯一一个被称呼洗礼名而不是姓氏的男孩儿。
3、Just as the teacher plays the role of leader in the classroom, so does the headteacher play a leadership role in the school.
在课堂上老师扮演着领导者的角色，同样，在学校里校长也充当着领导者的角色。
4、She is considered the best in the school.
全校数她功课好。
5、The pupils assembled [ were assembled] in the school hall.
学生在礼堂会集。
in the school=at the school在学校
前者表示的是学校的功能，后者表示的是在学校这个地点本回答被提问者采纳
At school=in the school.都是指学生在学校上课。
At school可以指很多in the school，只可以指某一所学校。
In the school=at school可以指教师或职员在学校里上班。