although 英[ɔ:lˈðəu] 美[ɔlˈðo]
conj. 虽然; 尽管; 但是; 然而;
[例句]Although he is known to only a few, his reputation among them is very great
虽然知道他的人不多，但他在这些人中名声却很响。
despite 英[dɪˈspaɪt] 美[dɪˈspaɪt]
prep. 不管; 虽有; 尽管（自己）不愿意; 不在乎;
n. 侮辱; 憎恨; 怨恨; 轻蔑的拒绝或不承认;
[例句]Despite a thorough investigation, no trace of Dr Southwell has been found
尽管进行了彻底的调查，还是没有发现索思韦尔博士的任何踪迹。
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